Madeira Airport Airlines
| Airlines | Destinations |
|---|---|
| Austrian Airlines | Seasonal: Vienna |
| Avion Express | Seasonal charter: Vilnius |
| Azores Airlines | New York–JFK, Ponta Delgada, Toronto–Pearson |
| Binter Canarias | Gran Canaria, Porto Santo, Tenerife–North Seasonal: Fuerteventura, Lanzarote, Marrakesh, Tenerife–South |
| British Airways | London–Heathrow |
| Condor | Düsseldorf, Frankfurt, Hamburg, Leipzig/Halle, Munich |
| easyJet | Berlin, Bristol, Lisbon airport, London–Gatwick, Lyon, Manchester, Milan–Malpensa, Paris–Charles de Gaulle,Porto |
| Edelweiss Air | Zürich |
| Enter Air | Seasonal charter: Katowice, Vilnius |
| EuroAtlantic Airways | Seasonal charter: Caracas |
| Eurowings | Düsseldorf Seasonal: Cologne/Bonn, Hamburg, Prague, Stuttgart |
| Eurowings Discover | Frankfurt, Munich |
| Finnair | Seasonal: Helsinki |
| Iberia | Madrid Seasonal: Barcelona, Bilbao, Málaga (begins 18 July 2023), Santiago de Compostela, Palma airport, Valencia (begins 18 July 2023) |
| Jet2.com | Birmingham, Bristol, East Midlands, Edinburgh, Glasgow, Leeds/Bradford, Liverpool (begins 1 May 2024), London–Stansted, Manchester, Newcastle upon Tyne |
| Lufthansa | Frankfurt, Munich |
| Luxair | Luxembourg |
| Norwegian Air Shuttle | Oslo Seasonal: Copenhagen |
| Ryanair | Beauvais, Bergamo, Charleroi, Dublin, Lisbon, London–Stansted, Manchester, Marseille, Nuremberg, Porto |
| Scandinavian Airlines | Seasonal: Stockholm–Arlanda |
| Smartwings | Seasonal: Prague, Brno |
| Sundair | Seasonal: Berlin |
| Swiss International Air Lines | Seasonal: Geneva |
| TAP Air Portugal | Lisbon, Porto |
| TAROM | Seasonal charter: Bucharest |
| Transavia | Amsterdam, Lyon, Nantes, Paris–Orly, Porto (resumes 4 November 2023) |
| TUI Airways | Birmingham, Manchester |
| TUI fly Belgium | Brussels |
| TUI fly Deutschland | Düsseldorf, Frankfurt, Hannover, Munich, Stuttgart |
| TUI fly Netherlands | Seasonal: Amsterdam |
| Wizz Air | Katowice, Rome–Fiumicino (begins 6 September 2025),Vienna Seasonal: Budapest, Warsaw–Chopin |